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A total of 212 Spanish smokers completed a Spanish version of a smoking questionnaire based on the Smoking Consequences Questionnaire—Adult (A. L. Copeland, T. H. Brandon, & E. P. Quinn, 1995) and a nicotine dependence (ND) measure. Confirmatory factor analysis results supported an a priori defined 8-factor structure. The results also indicated good internal consistency for the instrument and the scales derived from each factor. Positive outcome smoking expectancies scales were significantly and substantially associated with ND scores. Also, after controlling for the influence of ND, the authors found higher smoking expectancies in women than in men in (a) weight control, (b) craving reduction and addictiveness, and (c) negative-affect reduction. The results support the instrument's construct validity.