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This study evaluated the validity of the Desired Effects of Drinking Scale (DEoDS) with a late adolescent sample. This brief measure (37 items) was designed to assess reasons for drinking across 9 domains. Across a culturally diverse sample of late adolescents (ages 18-20 years), this measure evidenced high internal consistency, particularly when all items were summed in 1 full-scale score. Contrary to the factors found with adults, 8 factors emerged with this sample. No differences were found by culture, providing initial evidence for the cross-cultural validity of this measure. In addition, gender differences emerged for only 1 factor. Overall, the results provide empirical support for the use of this measure to assess late adolescents' and emerging adults' reasons for drinking.