TOPIRAMATE ATTENUATES A TRANSIENT LEARNING DEFICIT AFTER LESIONS INDUCING INTRACEREBRAL HEMORRHAGE1

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Abstract

28 male Long-Evans rats prepared with lesions of the middle cerebral artery displayed deficits in spatial navigational learning in a simple version of the Morris Water Maze task not seen in animals prepared with the same injury but administered 4 treatments with topiramate after surgery.

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