This study sought to explore the sex and cultural differences in satisfaction with life between undergraduate men and women recruited from four Arab countries, i.e., Egypt, Kuwait, Lebanon, and Qatar (N = 1,322); ages ranged from 18 to 27 years. The participants responded to the Arabic version of the Satisfaction with Life Scale. Egyptian and Lebanese women obtained significantly higher mean scores on satisfaction with life than did their male counterparts, whereas there were no significant sex differences in the Kuwaiti and Qatari samples. For men, the Qatari and Kuwaiti samples obtained the high mean scores on satisfaction with life, whereas the Egyptian and Lebanese samples obtained the low mean scores. For women, the Qatari sample had the higher mean score, whereas the Egyptian sample obtained the lowest mean score. The results were explained in light of the positive association between gross domestic product and satisfaction with life.