Hashimoto encephalopathy: literature review

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Excerpt

Hashimoto encephalopathy (HE), also known as steroid‐responsive encephalopathy, is associated with autoimmune thyroiditis and presents with encephalopathy and elevations in antithyroid antibodies without brain tumor, stroke, or infection of the central nervous system.1 Brain and colleagues reported the first case of HE in 1966. This first case presented with hallucinations, tremor, agitation, altered mental status, and elevated thyroid antibodies. HE was eventually diagnosed after confirmation of Hashimoto's thyroid disease by biopsy.2 Since then, more than 200 cases have been reported.3 Although the majority of the cases have good outcomes,3 death and status epilepticus due to HE have been reported.
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