This study reports the recent experience in the management of scoliosis in Down’s syndrome. Curve patterns, progression in brace, and surgical outcomes were recorded. Cardiac surgery history was compared between children with and without scoliosis. Out of 581 children with Down’s syndrome, 62 children had scoliosis. The mean age of the children was 13.8 years. The mean magnitude was 31°. Bracing was successful in five of seven patients. Ten children had posterior spinal fusion with follow-up of 2.6 years (1–7.3). One deep wound infection was recorded with no revision. No difference was found in cardiac surgery history between children with and without scoliosis. Level of Evidence: Type IV – prognostic and therapeutic study.