CORRInsights®: T1ρ Hip Cartilage Mapping in Assessing Patients With Cam Morphology: How Can We Optimize the Regions of Interest?
The utility of parametric mapping as a biomarker for early chondral-matrix depletion has been established, with multiple techniques of varying clinical feasibility currently available and/or in development [4, 5, 7]. T1ρ provides good sensitivity for changes in chondral proteoglycan content with a reasonable scan time and without the administration of intravenous contrast. It is a particularly promising technique for detecting early chondral-matrix depletion in the clinical setting before those changes become evident on standard MRI sequences [7, 12]. The identification of at-risk cartilage may allow for timely intervention aimed at joint preservation .