Closing-in is Related to Daily Living Functioning in Patients With Mild-to-Moderate Alzheimer Disease

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In Alzheimer disease (AD) progressive functional impairments occur early and considerably impact on quality of life,1 involving “basic activities of daily living” (BADLs) related to personal maintenance, such as eating or grooming, and “instrumental activities of daily living” (IADLs), such as telephone use or housekeeping. Several studies showed that impairment in BADLs would be related with dementia severity and frontal-executive dysfunctions, whereas decline in IADLs would be more specifically related to frontal-executive dysfunctions.

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