Neurosarcoidosis: unusual presentations and considerations for diagnosis and management

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Abstract

Background

Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%–15% of cases. Any part of the nervous system can be affected by sarcoidosis.

Cases

Herein we describe three unusual patient presentations of neurosarcoidosis, one with optic neuritis, a second with hydrocephalus and a third with cervical myelopathy.

Conclusions

We include pertinent details about their presentations, imaging findings, pathology, management and clinical course.

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