The gut microbiome takes center stage in critical care
How does the microbiome change in critically ill patients and how might this be leveraged therapeutically? Research questions like these take center stage in the intensive care research arena [1,2]. In the coming years, we can expect more studies on how the human microbiome – the collection of all genomes of all microbes in an ecosystem  – affects the health of our most vulnerable patients. In this issue of Current Opinion in Critical Care, researchers review current knowledge on the microbiome's effects on multiorgan dysfunction syndrome (MODS) and give a perspective on how microbiota-targeted therapies could potentially be utilized on the ICU [4,5].