Prostaglandin Injection After Arterial Compromise Related to Hyaluronic Acid Filler

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Injectable fillers have been used for restoring tissue volume or for rejuvenating facial wrinkles. The filler material used should be biocompatible, safe, and resistant to infection. Also, it should fix the adjacent tissues and maintain their volume. Although natural materials were initially used, biosynthetic materials are now the most commonly used fillers. Hyaluronic acid (HA) is composed of linear polymeric dimers of N-acetylglucosamine and glucuronic acid.1 The injection of HA filler is normally well tolerated, and the few soft tissue adverse effects tend to be mild and transient. Vascular complications are the main immediate adverse event of these treatments, producing discoloration or blanching of the affected tissues, with permanent sequels such as necrosis in some cases.
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