Case Report of Midazolam Withdrawal–Induced Catatonia in a 9-Year-Old Patient

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Abstract

Benzodiazepine withdrawal–induced catatonia is a rare phenomenon in the adult population and has never been reported in a pediatric patient. We present a 9-year-old boy who exhibited catatonia symptoms following discontinuation of a midazolam infusion in the pediatric intensive care unit. The pediatric anesthesia acute pain team was consulted. When the patient’s altered mental status could not otherwise be explained, benzodiazepine withdrawal–induced catatonia was considered. A dose of 2 mg intravenous lorazepam was given and the patient’s symptoms dramatically improved within 5 minutes of administration. The patient was successfully treated with an oral diazepam taper.

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