sfinx: an R package for the elimination of false positives from affinity purification-mass spectrometry datasets

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Abstract

Summary:

We describe sfinx, an R package providing access to the straightforward filtering index (SFINX) for the separation of true positive from false positive protein interactions in affinity purification - mass spectrometry datasets. This package maintains the reliability and user-friendliness of the SFINX web site interface but is faster, unlimited in input size, and can be run locally within R.

Availability and Implementation:

The sfinx R package is available for download at the comprehensive R archive network (CRAN) https://cran.r-project.org/web/packages/sfinx/ under the Apache License 2.0.

Contact:

sven.eyckerman@vib-ugent.be or kevin.titeca@gmail.com

Supplementary information:

Supplementary data are available at Bioinformatics online.

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