A Study on the Etiology, Severity, and Mortality of 3260 Patients With Acute Pancreatitis According to the Revised Atlanta Classification in Jiangxi, China Over an 8-Year Period

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Abstract

Objectives

Currently, the epidemiology of acute pancreatitis (AP) according to the Atlanta classification 2012 is rare. Thus, we aim to evaluate the etiology, severity, and mortality of AP according to Atlanta classification 2012 in Jiangxi, China.

Methods

We analyzed 3260 hospitalized patients between 2005 and 2012 from AP database. The severity was classified by the Atlanta classification 2012.

Results

3260 patients were admitted. Cholelithiasis (58.7%), hyperlipidemia (14.3%), and alcohol (4.5%) were the top 3 etiologies. Besides, in 16.7% of patients, the etiology still unexplained. 1238 patients (38.0%) were categorized as mild, 1551 (47.6%) as moderate, and 471 (14.4%) as severe acute pancreatitis. Hyperlipidemia and alcohol were the more common cause in men, especially the younger and middle aged, whereas cholelithiasis were the more common cause in women, especially the elderly. The overall mortality of AP was 1.2% and 8.5% in severe acute pancreatitis. Meanwhile, both severe idiopathic and hyperlipidemic pancreatitis had significantly higher mortality rate than severe biliary pancreatitis.

Conclusions

Cholelithiasis was the main etiology in Jiangxi, China, and hyperlipidemia ranked second. There were different etiological proportion according to age, sex, and severity. Furthermore, the higher mortality rate occurred in severe idiopathic and hyperlipidemic pancreatitis, although there was no clear association between mortality and age.

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