LASER server: ancestry tracing with genotypes or sequence reads

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Abstract

Summary:

To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results.

Availability and Implementation:

The LASER server is freely accessible at http://laser.sph.umich.edu/

Contact:

dtaliun@umich.edu or wangcl@gis.a-star.edu.sg

Supplementary information:

Supplementary data are available at Bioinformatics online.

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