90Y Liver Radioembolization Imaging Using Amplitude-Based Gated PET/CT

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Abstract

The usage of PET/CT to monitor patients with hepatocellular carcinoma following 90Y radioembolization has increased; however, image quality is often poor because of low count efficiency and respiratory motion. Motion can be corrected using gating techniques but at the expense of additional image noise. Amplitude-based gating has been shown to improve quantification in FDG PET, but few have used this technique in 90Y liver imaging. The patients shown in this work indicate that amplitude-based gating can be used in 90Y PET/CT liver imaging to provide motion-corrected images with higher estimates of activity concentration that may improve posttherapy dosimetry.

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