Antihypertensive treatment-induced changes in arterial stiffness: Which artery? Which method?
From a physiology point of view and by its definition, the arterial tree should be one of the main – if not the ultimate – target organ of arterial hypertension. Indeed, arterial hypertension is associated with both functional and structural changes in small and large arteries, as well as, in the capillary bed . These alterations include endothelial dysfunction, capillary rarefaction, arterial remodelling and stiffening . Hypertension is therefore considered as a major player in the ‘early vascular ageing’ process as well as in advanced arterial disease .