Patients with drug-resistant focal epilepsy who lack structural abnormalities on MRI constitute a challenge in presurgical work-up. A longitudinal single-centre study of long-term seizure outcomes in patients with nonlesional epilepsy showed that 59% of the cohort was free from disabling seizures 10 years after resective epilepsy surgery. These results are encouraging and valuable for patient counselling.
Refers to Kim, D. M. et al. Surgical treatment of nonlesional neocortical epilepsy: long-term longitudinal study. JAMA Neurol.http://dx.doi.org/10.1001/jamaneurol.2016.4439 (2017)