DOI: 10.1097/QAD.0000000000001391
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PMID: 28272140
Issn Print: 0269-9370
Publication Date: 2017/03/27
HIV-infected children with hepatomegaly and ascites: is there something more than an infection?
Ankur Kumar Jindal; Jasmina Ahluwalia; Avinash Sharma; Sumeet Dhawan; Karalanglin Tiewsoh; Deepti Suri; Anindita Sinha; Akshay Saxena; Surjit Singh
+ Author Information
Author Information: Department of Paediatrics, Advances Pediatrics Centre
Excerpt
HIV infection is known to predispose to venous thromboembolism (VTE), the risk ranging from 2% to 10% in adults [1]. A thrombotic state occurs because of abnormalities of coagulation system and platelet activation, endothelial dysfunction, opportunistic infections and antiretroviral therapy (ART) [2]. However, there are only a few reports of thrombosis in HIV-infected children [3–5] and, to the best of our knowledge, portal vein thrombosis has never been reported [6–8]. We report two children who developed this very uncommon complication.
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