Successful pregnancy in an HIV-positive kidney transplant recipient

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Excerpt

Approximately 40% of HIV-positive patients with end-stage kidney disease (ESKD) in the United Kingdom are women, many of them of reproductive age [1]. Advances in antiretroviral and immunosuppressive therapy have enabled kidney transplantation in this population [2,3]. Although the majority of pregnancies in kidney transplant recipients are successful, transplantation confers a substantially greater risk of obstetric complications, including prematurity, pre-eclampsia, foetal distress and intrauterine growth restriction, compared with the general population [4,5]. To our knowledge, no pregnancies have been reported in women with ESKD secondary to HIV with kidney allografts. Here, we report two successful pregnancies in an HIV-positive kidney transplant recipient.

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