Gene therapy, a promising treatment for familial hypercholesterolaemia

    loading  Checking for direct PDF access through Ovid


Cardiovascular diseases especially coronary heart disease (CHD) is a primary cause of death worldwide [1]. Epidemiological studies have shown that smoking, hypertension, diabetes and high plasma concentration of LDL cholesterol (LDL-C) are strongly associated with CHD [2]. Disorders of extremes of LDL-C such as familial hypercholesterolaemia indicate a causal relationship between LDL-C and CHD [3].
    loading  Loading Related Articles