Liver Transplantation: Candidate Selection and Organ Allocation in the United States

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Liver transplantation (LTx) is life-saving therapy for a variety of end-stage liver diseases, including cirrhotic, neoplastic, and metabolic disorders. As the cohort of patients with a disease process benefiting from LTx grows, the number of patients added to the waiting list per year continues to outstrip the number of transplants performed. It is this imbalance in supply and demand for donor livers that has led to the ongoing need for refinement of the systematic process in which donor livers are given to recipients: donor allocation.
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