Submental Alopecia at Deoxycholic Acid Injection Site

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Deoxycholic acid (KYBELLA, ATX-101) is indicated for improvement in the appearance of moderate-to-severe convexity or fullness associated with preplatysmal submental fat in adults. Common adverse reactions include injection site edema/swelling, hematoma, pain, numbness, erythema, and induration.1 Here, the authors present the cases of 2 patients who developed submental alopecia localized to deoxycholic acid injection sites. To the authors' knowledge, alopecia is not currently reported in the literature as an adverse reaction.
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