A case report: Liraglutide as a novel treatment option in late dumping syndrome

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Abstract

Rationale:

Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging.

Patient concerns:

New-onset postsurgical late dumping syndrome after Toupet fundoplication.

Diagnoses:

Sigstad Score, OGTT, CGM.

Interventions:

Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg).

Outcomes:

Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events.

Lessons:

Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.

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