Cpipe: a comprehensive computational platform for sequence and structure-based analyses of Cysteine residues

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Abstract

Summary:

Due to their chemical plasticity, Cysteine residues (Cys) can serve many different functions. Identification and classification of reactive Cys isn't a trivial job: currently, no available tool exists for an all-round, comprehensive (inclusive of all different functional types) analysis of Cys; herein we present a computational platform called Cpipe, dedicated to this task: it implements state-of-the art protocols, elaborating and displaying a wealth of information, sufficiently orthogonal to allow a thorough evaluation of all major aspects of Cys reactivity.

Availability and Implementation:

Cpipe is implemented in Python and freely available at http://cpipe.explora-biotech.com/cpipe/start.py. All major browsers are supported.

Contact:

s.marino@explora-biotech.com

Supplementary information:

Supplementary data are available at Bioinformatics online.

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