We thank Vallabhajosyula et al (1) for their interest in our study (2). We completely agree with their comment that Sequential Organ Failure Assessment (SOFA) score, inotrope score, Survival After Venoarterial Extracorporeal Membrane Oxygenation (SAVE) score, and evidence of end-organ hypoperfusion, anoxic brain injury, stroke work, and location of myocardial infarction are precise and accurate predictors of outcome in critical illness. As we already explained in our published article, however, our database lacked these data (2). Instead, we used disease severity–related factors including: etiology; use of catecholamines, antiarrhythmic agents, and sodium bicarbonate; percutaneous coronary intervention; coronary artery bypass grafting; and continuous renal replacement therapy. There was no significant difference in the occurrence rate of complications between the group undergoing intraaortic balloon pumping combined with venoarterial extracorporeal membrane oxygenation (VA-ECMO) and the group undergoing VA-ECMO alone.
We agree with the comment by Vallabhajosyula et al (1) that our risk adjustment may have been incomplete owing to a lack of data, and we hope they themselves will successfully construct a perfect database including SOFA, inotropes, SAVE, and others.