Reply: Effectiveness of Autologous Fat Grafting in Adherent Scars
Some remarks about the content of the authors’ letter could be made, as some references appear to be interesting choices. The cited study by Markman et al. is a decent study performed in 1987 that describes the anatomy of subcutaneous tissue located on the trunk and lower extremity. Interestingly, the authors state that this study highlights the regenerative qualities of fat. In addition, the authors positively mention that they performed lipofilling in numerous scar cases, although the corresponding reference by Portincasa et al. represents a study focusing on the adaptation of fasciocutaneous free flaps after being transferred to a recipient area. Finally, a previous letter of the research group—the article by Annacontini et al.—is cited, which commented on a prospective study that evaluated surgical excision and adjuvant irradiation for therapy-resistant keloids. It seems that keloidal treatment is not particularly related to the topic of lipofilling or fat grafting. Thus, after reading the current letter by the authors, it is considered that it is quite undesirable in scientific research to provide the reader with confusing references. Moreover, as letters are usually not peer reviewed, they should probably not contain original or primary data, as also supplied by the authors.