Cell-Intrinsic Defense at the Epithelial Border Wall:SalmonellaPays the Price

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Abstract

Within the gut,Salmonella-infected enterocytes are expelled into the lumen, limiting pathogen replication. In this issue ofImmunity,Rauch et al. (2017)expand our understanding of this cell-intrinsic response by characterizing the genetic determinants that control the expulsion and death of epithelial cells.

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