A case of cerebral hyperperfusion following spontaneous recanalization of occluded middle cerebral artery: Reperfusion injury or true cerebral hyperperfusion syndrome?

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Abstract

Background:

Cerebral hyperperfusion syndrome (CHS) and reperfusion injury are distinct pathological phenomena.

Case summary:

We present the case of a young ischemic stroke patient with middle cerebral artery (MCA) occlusion and spontaneous recanalization. Follow-up transcranial Doppler ultrasound showed high velocity flow in the left MCA, and neuroimaging revealed infarction, brain edema, artery dilatation, and hyperperfusion, consistent with both CHS and reperfusion injury.

Conclusion:

In cases with signs of both CHS and reperfusion injury, we speculate that CHS may be both a contributor to and a manifestation of reperfusion injury.

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