Severe pulmonary embolism managed with high-flow nasal cannula oxygen therapy

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High-flow nasal cannula oxygen therapy (HFNC) is a cornerstone treatment of respiratory failure 1–5. Its superiority upon noninvasive ventilation (NIV) and conventional oxygen therapy is established for mortality and avoidance of intubation in the most hypoxaemic patients 1. Various mechanisms explain the beneficial effects of HFNC on oxygenation 6; among these, a positive end-expiratory pressure has been measured 7. Few cases of pulmonary embolism (PE) treated with HFNC have been reported 3,8, among mixed aetiologies of acute respiratory failure (ARF).

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