DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia

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Abstract

Motivation:

Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.

Results:

DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.

Availability and Implementation:

The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.

Contact:

ronan.mt.fleming@gmail.com

Supplementary information:

Supplementary data are available at Bioinformatics online.

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