Localized Cutaneous Argyria From a Nasal Piercing Successfully Treated With a Picosecond 755-nm Q-Switched Alexandrite Laser

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Localized argyria is characterized by permanent blue to slate-gray discoloration of skin and/or mucous membranes due to cutaneous impregnation by aerosolized silver particles, often from occupational, topical (silver sulfadiazine), or percutaneous (piercings and acupuncture) exposure.1 Although topical therapy is ineffective, nanosecond 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser therapy can be safe and effective. There has been only 1 previous report, however, of successful treatment of cutaneous localized argyria with picosecond alexandrite laser devices.
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