Counting all k-mers in a given dataset is a standard procedure in many bioinformatics applications. We introduce KMC3, a significant improvement of the former KMC2 algorithm together with KMC tools for manipulating k-mer databases. Usefulness of the tools is shown on a few real problems.Availability and implementation:
Program is freely available at http://sun.aei.polsl.pl/REFRESH/kmc.Contact:
Supplementary data are available at Bioinformatics online.