HIV prevention: response to pre-exposure prophylaxis failure with tenofovir disoproxil

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We read with interest the recent article published in AIDS by Streeck et al.[1], highlighting a case of HIV pre-exposure prophylaxis (PrEP) failure in a gay man who was seemingly adherent to tenofovir-diphosphate (TDF) therapy for suppression of hepatitis B but who still acquired HIV.

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