Understanding Spontaneous Conversion: The Case of the Ly6C− Monocyte

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Abstract

Mouse blood monocytes include two main subsets usually discriminated by the expression of the Ly6C surface marker. The study by Mildner et al. (2017) in this issue of Immunity clarifies the transcriptional circuits controlling the generation of Ly6C− cells from their obligate precursors, the Ly6C+ monocytes.

Mouse blood monocytes include two main subsets usually discriminated by the expression of the Ly6C surface marker. The study by Mildner et al. (2017) clarifies the transcriptional circuits controlling the generation of Ly6C− cells from their obligate precursors, the Ly6C+ monocytes.

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