Transient ischemic attack and ischemic stroke patients with or without prior stroke

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A history of stroke is not uncommon in patients with transient ischemic attack (TIA) and ischemic stroke (IS). In recent TIA cohorts, 12%‐23% of patients had had a previous stroke,1 whereas in patients with ischemic stroke (IS) this proportion ranged from 18 to 23%.1
Comparative data on patients with first‐time or recurrent cerebrovascular events are scant. In a Danish community‐based study on patients with both ischemic and hemorrhagic stroke, recurrent stroke was associated with male sex, a history of TIA, atrial fibrillation (AF), and hypertension compared to first‐time events.9 In a Norwegian hospital‐based study on patients with ischemic stroke only, an association of recurrent events to male sex, age, hypertension, AF, large‐vessel disease, and leukoaraiosis on computed tomography was demonstrated.10 We did not find any comparative report on patients with TIA with or without a history of stroke.
Based on data from a large national TIA and stroke register, we aimed to compare TIA and IS patients with versus without a prior stroke regarding patient characteristics, risk factors, and secondary preventive medical treatment at discharge.

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