For chief nursing officers, volatility has become an expected characteristic of the professional landscape. Recent studies indicate that this volatility is likely to continue for at least the next decade. For chief nursing officers caught in an organizational crisis, the thought of leaving the leadership ranks triggers professional angst and a range of personal emotion. This article examines the most common reasons chief nursing officers leave their positions and how they can take steps to rebound. It also explores the tools and resources that can positively affect these monumental transitions, whether voluntary or involuntary.