BreakPoint Surveyor: a pipeline for structural variant visualization

    loading  Checking for direct PDF access through Ovid

Abstract

Summary:

BreakPoint Surveyor (BPS) is a computational pipeline for the discovery, characterization, and visualization of complex genomic rearrangements, such as viral genome integration, in paired-end sequence data. BPS facilitates interpretation of structural variants by merging structural variant breakpoint predictions, gene exon structure, read depth, and RNA-sequencing expression into a single comprehensive figure.

Availability and implementation:

Source code and sample data freely available for download at https://github.com/ding-lab/BreakPointSurveyor, distributed under the GNU GPLv3 license, implemented in R, Python and BASH scripts, and supported on Unix/Linux/OS X operating systems.

Contact:

lding@wustl.edu

Supplementary information:

Supplementary data are available at Bioinformatics online.

Related Topics

    loading  Loading Related Articles