Updates in Ocular Surface Tumor Diagnostics
Ocular surface tumors represent a range of conditions, from benign to malignant lesions. They originate from a variety of cell types, forming epithelial, melanocytic, lymphoid, leukemic, fibrous, lipomatous, and other lesions. The most common malignant tumors of the cornea and conjunctiva are ocular surface squamous neoplasia (OSSN), conjunctival melanoma (CM), and conjunctival lymphoma (CL).1 Each of these tumors arises from a similar-appearing premalignant lesion or can resemble a premalignant lesion. Differentiating between benign and malignant lesions, as well as between these 3 malignant conditions, can sometimes present a clinical challenge. However, accurate diagnosis is paramount because of the differences in treatment of these lesions. In this review, we will highlight the various modalities available for the diagnosis of conjunctival tumors and in particular for these 3 most common malignant tumors.