Brace Success as Related to Curve Type, Compliance, and Maturity in Adolescents with Idiopathic Scoliosis: Commentary on an article by Rachel M. Thompson, MD, et al.
The study provides convincing evidence that bracing with a TLSO is more effective for lumbar-dominant curves than for thoracic-dominant curves. The rate of reaching the surgical threshold was 15.4% for lumbar-dominant patterns compared with 34.1% for thoracic-dominant patterns. Compliance, defined as wearing the brace >12.9 hours/day, did enhance the treatment effect for both patterns, reducing the rate of those reaching the surgical threshold to approximately 30% for thoracic-dominant curves and approximately 5% for lumbar-dominant curves. Therefore, considering that the failure rate in the BrAIST observation group was 58%, one can see that bracing is effective in treating both thoracic-dominant and lumbar-dominant scoliosis. An exception may be curves with the mLenke-II pattern, in which a 54.5% rate of reaching the surgical threshold was found.
At least 10 of the original 222 patients were excluded from the trial for losing or failing to wear the brace and only 85 (51%) of 168 patients in the cohort wore the brace the requisite time of >12.9 hours/day, underscoring the demanding nature of brace treatment for adolescent boys and girls. However, the study reinforces the body of literature showing that compliance is important for success. Maxim Integrated Thermochron i-Buttons or similar devices can be used to monitor the patients’ time in the brace and to counsel the patients and their parents. These devices are commercially available, and practitioners managing these patients should consider adopting such devices.
Scoliosis is not a static condition, and the follow-up of patients after brace completion and beyond Risser stage 4 revealed that approximately 33% of the curves had progressed >5° and 22% had progressed to ≥50° at the last assessment (a mean of 22 months after brace cessation). The progression rate was similar for both thoracic-dominant and lumbar-dominant curves. These longer-term results must be evaluated with caution, since 18% of the cohort was lost to follow-up after reaching the end points for bracing.
Several obvious questions on the use of the TLSO for treatment of adolescent idiopathic scoliosis remain. Can success be predicted by flexibility or “in-brace correction”? This study suggests that flexibility is important, as the patients with a thoracic-dominant curve who demonstrated a conversion to a lumbar-dominant curve had a greater success rate with bracing.