Viscoelastic Testing of Coagulation

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Excerpt

Coagulopathy associated with trauma exists in one third of severely injured patients upon presentation to hospital. Our understanding of trauma-induced coagulopathy has increased significantly over the past decade.1–3 The cell-based theory of hemostasis has replaced the classic coagulation cascade proposed by Macfarlane in 1964 and emphasizes tissue factor (TF) as the initiator of coagulation released locally secondary to endothelial damage.4,5 Viscoelastic measurement of coagulation is being increasingly used to guide resuscitation for both rationalization of blood product use and to monitor effectiveness.

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