MoDMaps3D: an interactive webtool for the quantification and 3D visualization of interrelationships in a dataset of DNA sequences

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Abstract

Summary:

MoDMaps3D (Molecular Distance Maps 3D) is an alignment-free, fast, computationally lightweight webtool for computing and visualizing the interrelationships within any dataset of DNA sequences, based on pairwise comparisons between their oligomer compositions. MoDMaps3D is a general-purpose interactive webtool that is free of any requirements on sequence composition, position of the sequences in their respective genomes, presence or absence of similarity or homology, sequence length, or even sequence origin (biological or computer-generated).

Availability and implementation:

MoDMaps3D is open source, cross-platform compatible, and is available under the MIT license at http://moleculardistancemaps.github.io/MoDMaps3D/. The source code is available at https://github.com/moleculardistancemaps/MoDMaps3D/.

Contact:

lila@uwaterloo.ca

Supplementary information:

Supplementary data are available at Bioinformatics online.

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