Issn Print: 1522-8517
Publication Date: 2017/10/19
Phase I study of oral sonidegib (LDE225) in pediatric brain and solid tumors and a phase II study in children and adults with relapsed medulloblastoma
Mark W Kieran; Julia Chisholm; Michela Casanova; Alba A Brandes; Isabelle Aerts; Eric Bouffet; Simon Bailey; Sarah Leary; Tobey J MacDonald; Francoise Mechinaud; Kenneth J Cohen; Riccardo Riccardi; Warren Mason; Darren Hargrave; Stacey Kalambakas; Priya Deshpande; Feng Tai; Eunju Hurh; Birgit Geoerger
Author Information: Pediatric Neuro-Oncology, Dana-Farber Boston Children’s Cancer Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, USA (M.W.K.); The Royal Marsden Hospital, Sutton, Surrey, UK (J.C.); Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (M.C.); Department of Medical Oncology, Azienda USL—IRCCS Institute of Neurological Science, Bologna, Italy (A.A.B.); Institut Curie and University Paris Descartes, Paris, France (I.A); Division of Haematology/Oncology at The Hospital for Sick Children, Toronto, Ontario, Canada (E.B.); Sir James Spence Institute of Child Health Royal Victoria Infirmary, Newcastle, UK (S.B.); Seattle Children’s Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, Washington, USA (S.L.); Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA (T.J.M.); The Royal Children’s Hospital, Children’s Cancer Center, Melbourne, Australia (F.M.); The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA (K.J.C.); Catholic University of the Sacred Heart, Rome, Italy (R.R.); Cancer Clinical Research Unit, Princess Margaret Cancer Centre, Toronto, Ontario, Canada (W.M.); Paediatric Oncology Unit, Great Ormond Street Hospital, London, UK (D.H.); Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA (S.K., P.D., F.T., E.H.); Gustave Roussy, Department of Pediatric and Adolescent Oncology, University Paris-Sud, Université Paris-Saclay, Villejuif, France (B.G.)
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