Influence of Refractive Status on the Higher-Order Aberration Pattern After Small Incision Lenticule Extraction Surgery

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Abstract

Purpose:

To study the effect of myopia on the pattern change in higher-order aberrations after small incision lenticule extraction.

Methods:

Sixty eyes of 60 patients were included: low myopia (≤−3.00 D), moderate myopia (−3.00 D to −6.00 D), and high myopia (≥−6.00 D). Total higher-order aberrations (tHOA), vertical coma (

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM1/v/2017-07-26T070947Z/r/image-tiff

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), horizontal coma (

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM2/v/2017-07-26T070947Z/r/image-tiff

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), and spherical aberration (

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM3/v/2017-07-26T070947Z/r/image-tiff

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) were measured preoperatively and at postoperative 3 months.

Results:

At the end of 3 months, tHOA changed significantly compared with the preoperative values (P < 0.05), except for

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM4/v/2017-07-26T070947Z/r/image-tiff

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and

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM5/v/2017-07-26T070947Z/r/image-tiff

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in the low myopia group. The change in

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM6/v/2017-07-26T070947Z/r/image-tiff

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,

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM7/v/2017-07-26T070947Z/r/image-tiff

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, and

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM8/v/2017-07-26T070947Z/r/image-tiff

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in the moderate group (−0.299, −0.175, and 0.108 μm) was 2.020, 4.861, and 4.696 times higher than the low group (−0.148, −0.036, 0.023 μm) (P = 0.002, 0.001, 0.001), respectively. The value in the high group (−0.331, −0.192, 0.154 μm) was 1.107, 1.097 (P = 0.478, 0.665), and 1.426 times (P = 0.047) higher than the moderate group. The degree of myopia was positively correlated with Δ

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM9/v/2017-07-26T070947Z/r/image-tiff

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(r = 0.447; P < 0.001) and Δ

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM10/v/2017-07-26T070947Z/r/image-tiff

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(r = 0.496; P < 0.001), and negatively correlated with ΔtHOA (r = −0.363, P = 0.004) and Δ

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM11/v/2017-07-26T070947Z/r/image-tiff

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(r = −0.599; P < 0.001).

Conclusions:

The study showed a different pattern of change in ocular aberrations after small incision lenticule extraction in patients with varying degrees of myopia. In patients with low myopia, there was no increase in

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM12/v/2017-07-26T070947Z/r/image-tiff

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or

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM13/v/2017-07-26T070947Z/r/image-tiff

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. In high myopia, however,

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JOURNAL/corne/04.02/00003226-201708000-00012/math_12MM14/v/2017-07-26T070947Z/r/image-tiff

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increased with the degree of myopia, whereas the rising rate of coma was slowing.

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