Surgery for lifesaving and disability-averting conditions is an effective and safe public health priority. Global health priorities traditionally focused on infectious disease in low-income and middle-income countries (LMIC). In the last decades, surgery and safe anesthesia have gained attention as essential, primary interventions to address injury and disease. My experiences in Asia, South America, and Africa have exposed me to a wide range of healthcare models of delivery, surgical providers, and funding sources [e.g., government, nongovernment organizations (NGOs), and academic partnerships]. Herein, I will frame the problem that global surgery seeks to address by telling a brief story of my observations in western Kenya, then introduce the key concepts of the international global surgery community's response to the problem [Lancet Commission for Global Surgery (LCoGS)], and outline the tasks that have been chosen to achieve these priorities.