Case of Presumed Transient Light-Sensitivity Syndrome After Small-Incision Lenticule Extraction

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To report the first presumed case of transient light-sensitivity syndrome (TLSS) after small-incision lenticule extraction (SMILE).


A 27-year-old male patient was treated for severe photophobic symptoms occurring 7 weeks after undergoing a bilateral SMILE procedure. His comprehensive ocular examination was unremarkable and his visual acuity was unaffected. Treatment was a month-long tapering dose of topical steroids.


Photophobic symptoms fully resolved after steroid treatment. TLSS related to SMILE mirrors TLSS after laser in situ keratomileusis in both onset and steroid responsiveness.


TLSS is a rare and minor complication of SMILE. Photophobic symptoms associated with post-SMILE TLSS are fully responsive to topical corticosteroids.

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