Breast liposarcoma with solitary metastasis to the pleura: A case report

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Breast cancer is the most prevalent malignancy in women worldwide. Our patient presented with a history of breast liposarcoma (LPS) and was found to have pleural metastasis during the initial workup.

Patient concerns:

The patient was complaining about chest pain and dyspnea that had persisted for a week.


After a full evaluation and histological diagnosis, she was diagnosed as metastatic breast LPS.


We adopted 6 cycles of pegylated liposomal doxorubicin (PLD) plus ifosfamide as 1st-line palliative chemotherapy, combined with local pleural effusion management.


The patient's symptoms were notably relieved, and both malignant metastatic lesions and pleural effusion were controlled.


Although metastatic breast LPS is rarely reported and incurable, more clinical experience and use of next-generation sequencing should be helpful in finding the effective treatment for metastatic LPS.

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