Comparison of Oropharyngeal and Nasopharyngeal Swab Specimens for the Detection ofMycoplasma pneumoniaein Children with Lower Respiratory Tract Infection

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Abstract

The oropharyngeal swab specimen was superior to the nasopharyngeal swab specimen for the detection of Mycoplasma pneumoniae in children with lower respiratory tract infection. The oropharyngeal loop-mediated isothermal amplification had 100% sensitivity and specificity compared with polymerase chain reaction testing, whereas the oropharyngeal rapid antigen detection test using immunochromatographic assay had relatively low sensitivity (66%) and reasonable specificity (90.7%).

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