Cryopyrin Cry

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1. Increase, with "up"
5. CRYOPYRIN DX
9. Security corp.
12. Corvette ___
13. Double reed instrument
14. Dusk, to Donne
15. Okla., before 1907
16. Bundle
17. Amiss
18. THERAPY TARGETING 11 OR 20 DOWN
21. Food type
22. Connect
24. Rest, in a way
26. CRYOPYRIN GENE
27. Stout, for example
30. ___ sad !
32. Beatty
33. CRYOPYRIN DX
35. Director Jean-___ Godard
36. Aims
37. Columnist Peggy
42. CRYOPYRIN SCAFFOLD
46. Gradeschool trio
47. Fishing, perhaps
48. Gulf V.I.P.
49. Measure abbr.
50. CRYOPYRIN DX
51. Giving
52. 180° from NNW
53. Clappers
54.
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