Antihypertensive therapy: strategic withdrawal or a mandatory life sentence?

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Conventional practice demands that once started drug therapy will be for life. Nobody, therefore, should initiate drug therapy for hypertension lightly. On the other hand, any clinical trial list testing antihypertensive treatments will recall withdrawing people from antihypertensive therapy during a run-in phase and finding that some did not achieve the blood pressure (BP) threshold for entry into the randomized phase of the study and remained normotensive off treatment.

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